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Circadian rhythm in the number of granulated vesicles in the pinealocytes of mice
TLDR
Melatonin, administered as daily intraperitoneal doses of 50 μg over a period of five days, was observed to increase markedly the number of pinealocytic granulated vesicles during the light period, but led during the dark period to a decrease in their numbers to levels below that of diluent-treated controls. Expand
Isolation and structure elucidation of bovine pineal arginine vasopressin: arginine vasotocin not identified.
TLDR
Large scale purification of bovine pineal neurohypophysial hormone-like substances which demonstrate mouse mammary milk-ejection activity (ME-activity) in vitro is undertaken. Expand
Presence of an antigonadotropic substance in rat pineal incubation media.
TLDR
The incubation media were observed to inhibit compensatory ovarian hypertrophy when administered as single intraperitoneal injections to Charles River CD-1 mice on the day of unilateral ovariectomy. Expand
Dietary fish oil delays puberty in female rats.
TLDR
Fish oil feeding did not affect growth as indicated by the lack of an observed effect on body weights or femur lengths, but GnRH concentration in the preoptic area/hypothalamus was significantly increased in the fish oil-fed rats and radioimmunoassable hypothalamic PGE2 was concomitantly reduced. Expand
A melatonin-free extract of bovine pineal with antigonadotropic activity.
TLDR
This treatment resulted in inhibition of compensatory ovarian hypertrophy (COH) that was comparable to the antigonadotropic effects of 30.0 μg of crystalline melatonin injected in the same manner. Expand
LH inhibitory properties of aqueous extracts of rat pineal glands.
TLDR
Crude aqueous extracts of rat pineal glands markedly inhibited the 24 and 48 hour postcastration rise of serum LH in mature male rats, indicating that some substance other than this indole may be responsible for the anti-LH property in aqueously extracts. Expand
Localization of a sheep pineal antigonadotropin.
TLDR
When injected into male and female Charles River CD-1 albino mice the low molecular weight fractions from Sephadex G-25, and after ultrafiltration the UM-05 residue of these fractions, demonstrated significant effects on the reproductive system. Expand
Inhibition of compensatory renal growth by indomethacin.
TLDR
Findings suggest renal prostaglandins may participate in the biological events leading to compensatory renal growth in adult male Sprague Dawley rats. Expand
Dietary fish oil interferes with renal arachidonic acid metabolism in rats: correlations with renal physiology.
TLDR
Dietary fish oil modifies glomerular and renal tubular function in rats, and worsens age-associated proteinuria and declines in GFR, which may reflect the impact of dietary fish oil on renal fatty acid composition and arachidonic acid metabolism. Expand
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