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Isolation of myelin basic protein–specific T cells predominantly from the memory T‐cell compartment in multiple sclerosis
Myelin antigen–reactive T cells have been implicated in the pathogenesis of multiple sclerosis (MS). Myelin‐reactive T cells can be isolated from control subjects as well as individuals who have MS.Expand
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Society for the Study of Amphibians and Reptiles: A fifty year history 1958 to 2007
-A new species of small, terrestrial Eleutherodactylus is described from a restricted area of interandean montane forest in central Ecuador. This species is most similar to E. orestes from southernExpand
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In vivo reduction of telomere length in human antigen‐reactive memory T cells
There is a reduction in the average telomere lengths of CD4+ "memory" T cells, defined by the CD45RO+ phenotype, compared to CD54RA+ "naive" T cells. However, other studies suggest that telomeraseExpand
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Isolation of CD45RO+, memory T cells recognizing proteolipid protein from neurologically normal subjects.
Previous studies provide evidence for in vivo activation of MBP-reactive T cells in subjects with multiple sclerosis. In general, in vivo activation occurs less frequently in healthy controlExpand
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Requirement for CD4+T Cells in the γδ T Cell Proliferative Response to Daudi Burkitt's Lymphoma
Abstract Daudi Burkitt's lymphoma cells stimulate the proliferation of Vγ2 Vδ2 T cells in human peripheral blood mononuclear cells (PBMC). Transfection studies have established that the γδ T cellExpand
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In vivo activation of myelin oligodendrocyte glycoprotein-specific T cells in healthy control subjects.
Autoreactive T cells are present in healthy subjects but are assumed not to induce overt disease due to lack of exposure to autoantigen or because of immune regulation. In EAE, activation of myelinExpand
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Induction of Vγ2 Vδ2 T cell proliferation by activated, antigen-specific CD4+ T cells and IL-2
Abstract Human γδ T cells respond to a wide range of ligands including some T lymphocyte cellular antigens associated with viral infection. In the present study we examined the participation of γδ TExpand
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Gamma delta T cells participate in the immune response against activated, myelin basic protein-specific, human T cells.
gamma delta T cells are over-represented in some multiple sclerosis (MS) parenchymal lesions and in the cerebrospinal fluid (CSF) of individuals with early MS. In this investigation we studied the TExpand
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Requirement for CD4+ T cells in the gammadelta T cell proliferative response to Daudi Burkitt's lymphoma.
Daudi Burkitt's lymphoma cells stimulate the proliferation of Vgamma2 Vdelta2 T cells in human peripheral blood mononuclear cells (PBMC). Transfection studies have established that the gammadelta TExpand
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