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Treatment of acute promyelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy.
INTRODUCTION Arsenic trioxide is effective and approved for treatment of relapsed or refractory acute promyelocytic leukemia (APL) cases resistant to all-trans retinoic acid (ATRA), but its effect onExpand
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Phase II study of single-agent arsenic trioxide for the front-line therapy of acute promyelocytic leukemia.
PURPOSE The long-term follow-up results of patients with acute promyelocytic leukemia (APL) treated with all-trans retinoic acid and chemotherapy show high cure rates. Several studies have shown highExpand
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Frequency of BCR-ABL fusion transcripts in Iranian patients with chronic myeloid leukemia.
BACKGROUND A specific chromosomal abnormality, the Philadelphia chromosome, is present in 90 - 95% of patients with chronic myeloid leukemia. The aberration results from a reciprocal translocation ofExpand
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Effects of chimerism on graft-versus-host disease, disease recurrence, and survival after HLA-identical marrow transplantation in Iran.
BACKGROUND The coexistence of recipient's and donor's hematopoietic systems after allogeneic marrow transplantation is called mixed chimerism. OBJECTIVE The objective of this study was to evaluateExpand
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Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran.
BACKGROUND The investigation of mutation patterns in oncogenes potentially can make available a reliable mechanism for management and treatment decisions for patients with colorectal cancer (CRC).Expand
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Communication with the Cancer Patient in Iran
Confrontation with death or its possibility is a horrible shock for most people, especially if this occurs as a result of a cancer diagnosis and if the patient is young and active or is for any otherExpand
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Continuous bladder irrigation prevents hemorrhagic cystitis after allogeneic hematopoietic cell transplantation.
Hemorrhagic cystitis is 1 of the most troublesome complications of hematopoietic cell transplantation conditioning regimens. We conducted a nonrandomized controlled clinical study to investigate theExpand
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Stem cell transplantation; Iranian experience.
From March 1991 through 31st December 2007, 2042 patients underwent stem cell transplantation at the Hematology-Oncology and Stem Cell Transplantation Research Center, affiliated to Tehran UniversityExpand
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Treatment of New Cases of Acute Promyelocytic Leukaemia by Arsenic Trioxide.
Purpose: Arsenic Trioxide approved for treatment of relapsed or refractory APL to ATRA. We studied the effects of Arsenic Trioxide as first line treatment of new cases of APL and their follow up.Expand
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Comparison of 60 and 80 mg/m2 of daunorubicin in induction therapy of acute myeloid leukaemia
For finding better method of acute myeloid leukaemia (AML) induction, we designed a prospective clinical trial to find a more effective regimen with least toxicity for induction therapy of AML.Expand
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