• Publications
  • Influence
The effects of gender and age on REM-related sleep-disordered breathing
Sleep disordered breathing occurring predominantly in rapid eye movement REM sleep (rapid-eye-movement-related sleep-disordered breathing, REM SDB) is present in 10 to 36% of patients undergoingExpand
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Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea
Background Obstructive sleep apnoea (OSA) is a heterogeneous disorder, and improved understanding of physiologic phenotypes and their clinical implications is needed. We aimed to determine whetherExpand
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The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study.
STUDY OBJECTIVES To determine whether sleep-disordered breathing (SDB) is associated with cardiac arrhythmia in a clinic-based population with multiple cardiovascular comorbidities and severe SDB. Expand
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Restless Legs Syndrome and Depression: Effect Mediation by Disturbed Sleep and Periodic Limb Movements.
OBJECTIVE To investigate an association between restless legs syndrome (RLS) and depression and to what extent sleep disturbance, periodic limb movements during sleep (PLMS), and antidepressantExpand
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Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea.
STUDY OBJECTIVES Determine the prevalence of, and clinical features associated with, a low respiratory arousal threshold (ArTH) among patients with obstructive sleep apnea (OSA), and to assessExpand
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Association of Incident Cardiovascular Disease With Periodic Limb Movements During Sleep in Older Men: Outcomes of Sleep Disorders in Older Men (MrOS) Study
Background— Periodic limb movements during sleep (PLMS) cause repetitive sympathetic activation and may be associated with increased cardiovascular risk. We hypothesized that PLMS frequency (periodicExpand
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Rapid eye movement-related sleep-disordered breathing: influence of age and gender.
BACKGROUND Sleep-disordered breathing (SDB) occurring during rapid eye movement (REM) sleep occurs more frequently in women than men. We sought to characterize REM SDB prevalence by gender and age toExpand
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Restless legs syndrome: relationship between prevalence and latitude
  • B. B. Koo
  • Medicine
  • Sleep and Breathing
  • 1 December 2012
PurposeRestless legs syndrome (RLS) has a broad worldwide prevalence between 0.01% and 18.3%. While differences in RLS definitions and data ascertainment methods account for some variability, otherExpand
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Restless Leg Syndrome Across the Globe: Epidemiology of the Restless Legs Syndrome/Willis-Ekbom Disease.
  • B. B. Koo
  • Medicine
  • Sleep medicine clinics
  • 1 September 2015
There are more than 50 epidemiologic studies measuring the prevalence of restless legs syndrome/Willis-Ekbom disease (RLS/WED) across 5 of the 6 inhabited continents (not Australia), most conductedExpand
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Blunted rise in brain glucose levels during hyperglycemia in adults with obesity and T2DM.
In rodent models, obesity and hyperglycemia alter cerebral glucose metabolism and glucose transport into the brain, resulting in disordered cerebral function as well as inappropriate responses toExpand
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