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Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain
One of the most challenging problems in modern neuroimaging is detailed characterization of neurodegeneration. Quantifying spatial and longitudinal atrophy patterns is an important component of thisExpand
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The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)
In this paper we report the set-up and results of the Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) organized in conjunction with the MICCAI 2012 and 2013 conferences. TwentyExpand
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A reproducible evaluation of ANTs similarity metric performance in brain image registration
The United States National Institutes of Health (NIH) commit significant support to open-source data and software resources in order to foment reproducibility in the biomedical imaging sciences.Expand
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N4ITK: Improved N3 Bias Correction
A variant of the popular nonparametric nonuniform intensity normalization (N3) algorithm is proposed for bias field correction. Given the superb performance of N3 and its public availability, it hasExpand
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Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration
All fields of neuroscience that employ brain imaging need to communicate their results with reference to anatomical regions. In particular, comparative morphometry and group analysis of functionalExpand
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The optimal template effect in hippocampus studies of diseased populations
We evaluate the impact of template choice on template-based segmentation of the hippocampus in epilepsy. Four dataset-specific strategies are quantitatively contrasted: the "closest to average"Expand
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Geodesic estimation for large deformation anatomical shape averaging and interpolation
The goal of this research is to promote variational methods for anatomical averaging that operate within the space of the underlying image registration problem. This approach is effective when usingExpand
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An Open Source Multivariate Framework for n-Tissue Segmentation with Evaluation on Public Data
We introduce Atropos, an ITK-based multivariate n-class open source segmentation algorithm distributed with ANTs (http://www.picsl.upenn.edu/ANTs). The Bayesian formulation of the segmentationExpand
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Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements
Many studies of the human brain have explored the relationship between cortical thickness and cognition, phenotype, or disease. Due to the subjectivity and time requirements in manual measurement ofExpand
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Nearly automatic segmentation of hippocampal subfields in in vivo focal T2-weighted MRI
We present and evaluate a new method for automatically labeling the subfields of the hippocampal formation in focal 0.4 × 0.5 × 2.0mm(3) resolution T2-weighted magnetic resonance images that can beExpand
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