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One hundred and twelve infected arthroplasties treated with ‘DAIR’ (debridement, antibiotics and implant retention): antibiotic duration and outcome
- I. Byren, P. Bejon, +5 authors A. Berendt
- The Journal of antimicrobial chemotherapy
- 31 March 2009
Objectives We describe treatment failure rates by antibiotic duration for prosthetic joint infection (PJI) managed with debridement, antibiotics and implant retention (DAIR). Methods We… Expand
NCL-CD10-270: a new monoclonal antibody recognizing CD10 in paraffin-embedded tissue.
CD10 (CALLA) antigen is expressed in a wide variety of epithelial and nonepithelial tissues, but its most significant application is in the diagnosis and classification of certain types of malignant… Expand
Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer.
Sections of formalin-fixed, paraffin-embedded tissue from 185 primary breast carcinomas were stained immunohistochemically using a polyclonal antibody against the c-erbB-2 oncoprotein. Positive… Expand
Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancer.
Of 221 patients with breast cancer of known epidermal growth factor receptor (EGFR) and oestrogen receptor (ER) status, 99 had developed recurrences during the period of follow-up (range 3-60 months,… Expand
p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin.
- C. Campbell, A. Quinn, Y. S. Ro, B. Angus, J. Rees
- Biology, Medicine
- The Journal of investigative dermatology
- 1 June 1993
Mutations of the p53 gene are the most common genetic abnormality described in human cancer; p53 mutations have recently been reported in more than half of the cases of squamous cell carcinomas of… Expand
Fidaxomicin Versus Vancomycin for Clostridium difficile Infection: Meta-analysis of Pivotal Randomized Controlled Trials
- D. Crook, A. Walker, +10 authors T. Peto
- Clinical infectious diseases : an official…
- 1 August 2012
Two recently completed phase 3 trials (003 and 004) showed fidaxomicin to be noninferior to vancomycin for curing Clostridium difficile infection (CDI) and superior for reducing CDI recurrences. In… Expand
Impact of tumor Epstein-Barr virus status on presenting features and outcome in age-defined subgroups of patients with classic Hodgkin lymphoma: a population-based study.
The association between tumor Epstein-Barr virus (EBV) status and clinical outcome in Hodgkin lymphoma (HL) is controversial. This population-based study assessed the impact of EBV status on survival… Expand
Hodgkin's disease in the elderly: a population‐based study
- G. Stark, K. Wood, F. Jack, B. Angus, S. Proctor, P. Taylor
- British journal of haematology
- 1 November 2002
Summary. This study evaluated the incidence and outcome of Hodgkin's disease (HD) in older patients using a population‐based approach. In total, 102 patients (52 men, 50 women) aged ≥ 60 years… Expand
Prognostic value of cytokine concentrations (tumor necrosis factor-alpha, interleukin-6, and interleukin-10) and clinical parameters in severe melioidosis.
- A. J. Simpson, M. Smith, +6 authors J. Prins
- The Journal of infectious diseases
- 1 February 2000
Raised serum concentrations of tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, or IL-10 are associated with mortality in patients with sepsis, but it is not known whether elevated… Expand
Epidermal growth factor receptor status of histological sub-types of breast cancer.
- J. Sainsbury, S. Nicholson, B. Angus, J. Farndon, A. Malcolm, A. Harris
- British Journal of Cancer
- 1 October 1988
The histological breakdown of a consecutive series of 264 surgically resected malignant lesions of the breast was studied. Oestrogen and epidermal growth factor receptor status was quantified and… Expand