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Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque.
TLDR
Centrifugation of heparinized human blood on discontinuous gradients of Ficoll-Hypaque resulted in the simultaneous separation of mononuclear leukocytes, granulocytes, and erythrocytes with high recovery of each cell type. Expand
Killing of Mycobacterium tuberculosis by neutrophils: a nonoxidative process.
TLDR
The mechanism by which M. tuberculosis is killed by neutrophils is independent of the oxygen metabolic burst, leading to the conclusion that patients with chronic granulomatous disease (CGD) have a defect in the NADPH oxidase pathway, causing their neutrophil to be unable to generate oxygen radicals. Expand
Effect of Mycobacterium tuberculosis-derived sulfolipid I on human phagocytic cells
TLDR
Sulfolipid I-induced changes in phagocytic cell function may be important in altering the ability of phagocytes to respond effectively to M. tuberculosis and may also cause exaggerated inflammatory responses. Expand
Defective initiation of oxidative metabolism in polymorphonuclear leukocytes.
TLDR
Evidence is provided that polymorphonuclear leukocytes have more than one mechanism for initiating oxidative metabolism, as shown in a two-year-old boy who had multiple episodes of bacterial infections. Expand
Effects of Mild Periodate Oxidation on Antibodies
Other effects of oxidation on rabbit antibody included an increase in electrophoretic mobility and a tendency to form aggregates. No change in the antigenic determinants of periodate oxidized RGG wasExpand
HOST FACTORS CAUSING INCREASED SUSCEPTIBILITY TO INFECTION IN PATIENTS WITH LAENNEC'S CIRRHOSIS
  • B. Andersen
  • Medicine
  • Annals of the New York Academy of Sciences
  • 1 April 1975
TLDR
The effects of cirrhosis on host-defense mechanisms that increase the risk of infection will be dealt with, but it will not cover the influences of acute alcoholic intoxication on these mechanisms. Expand
Important Variables in Granulocyte Chemiluminescence
Summary A CL system consisting of canine granulocytes stimulated with opsonized zymosan was used to examine factors which lead to variability in light production. Variability of CL response wasExpand
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