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Thiazole orange-induced c-di-GMP quadruplex formation facilitates a simple fluorescent detection of this ubiquitous biofilm regulating molecule.
It is demonstrated that c-di-GMP can form G-quadruplexes at low micromolar concentrations when aromatic molecules such as thiazole orange template the quadruplex formation, and this property of aromatic molecule-induced G- quadruplex formation is used to design a thiazoles orange-based fluorescent detection of this important signaling molecule.
New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3.
A series of cyclopentane derivatives represent promising starting points in the development of new anticancer agents for the treatment of hormone-dependent forms of cancer and other diseases where AKR 1C1 and AKR1C3 are involved.
Surface-Functionalized COMB Capacitive Sensors and CMOS Electronics for Vapor Trace Detection of Explosives
In this paper, we present a miniature detection system, which is able to detect and selectively recognize different vapor traces of explosives. It is based on surface-functionalized array of COMB
Metal-Catalysed Transfer Hydrogenation of Ketones
The focus of this review is devoted to chiral catalyst types which are capable of inducing high stereoselectivities, and Ruthenium complexes still represent the largest part of the catalysts, but other metals are rapidly penetrating this field.
Advances in Catalyst Systems for the Asymmetric Hydrogenation and Transfer Hydrogenation of Ketones
Hydrogenation of prochiral ketones using chiral transition-metal catalysts represents the cleanest way to access enantiomerically enriched secondary alcohols, which are important building blocks in