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  • Manfred Suckow, B von Wilcken-Bergmann, Benno Müller-Hill
  • Biology, Medicine
  • The EMBO journal
  • 1993 (First Published: 1 March 1993)
  • The bZIP regions of the eukaryotic transcription factors GCN4 and C/EBP have similar protein sequences but they recognize different DNA sequences. In order to understand their specificity, a vectorContinue Reading
  • Jennifer A Sartorius, Norbert Lehming, B. Kisters, B von Wilcken-Bergmann, Benno Müller-Hill
  • Biology, Medicine
  • The EMBO journal
  • 1989 (First Published: 1 April 1989)
  • Several lac repressor mutants have been isolated which repress beta-galactosidase synthesis in Escherichia coli up to 200-fold. They do so by binding specifically to particular symmetrical lac OcContinue Reading
    Two residues are invariant in all bZip basic regions: asparagine -18 and arginine -10 (we define the first leucine of the leucine zipper of GCN4 as +1). X-ray structures of two specific GCN4-DNAContinue Reading