B. van de Langerijt

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A 56 year old man was diagnosed with B-chronic lympho-cytic leukemia (B-CLL) in another hospital (RAI 4, BINET C, IGHV mutated; FISH: 59% of cells trisomy 12). Treatment was started with fludarabine, cyclophosphamide and alemtuzumab. The patient received pneumocystis jiroveci pneumonia prophylaxis and herpes prophylaxis with sul-phamethoxazole–trimethoprim(More)
OBJECTIVE To investigate the diagnostic value of transforming growth factor beta(1) (TGFbeta(1)), vascular endothelial growth factor (VEGF), urokinase-type plasminogen activator (uPA), and tissue-type plasminogen activator (tPA) in CSF for leptomeningeal metastasis (LM). METHODS The authors measured concentrations of biomarkers by ELISA in matched samples(More)
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