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DNA probes containing the switch region (S) associated with the human immunoglobulin heavy chain mu gene were used to investigate polymorphisms in the germ-line human DNA. Six polymorphisms, detected by a single restriction enzyme (Sst I) are described. Linkage studies in 29 families show that five of the six polymorphisms, although relatively unassociated(More)
A group of Taiwan aborigines, the Toroko, was typed for 21 classical genetic loci. This is part of an ongoing program aimed at a comprehensive study of Taiwan aborigines. In this first paper a short summary of historical, archeological, and anthropological data in the literature is made, and results of the present survey are compared with older results from(More)
The highly polymorphic system of serologically defined genetic markers on human IgG heavy chains (Gm allotypes) is second only to the HLA complex in terms of the large number of determinants, alleles, and haplotypes that can be used for analyses of disease associations and other genetic studies. However, present typing methods are based on the use of(More)
A new antibody, anti-Rh41, is described. This antibody was found prepartum in a multiparous, Caucasian female with no prior history of transfusions. Anti-Rh41 reacts with red blood cells from individuals with cis oriented C and e genes, but is nonreactive with cells possessing the products derived from individuals with cis-oriented Cw and e genes, a(More)
Red blood cells of 255 inhabitants of San Antonio Palopo, an Indian community on the eastern shore of Lake Atitlán, Guatemala, have been typed with antiserum.. to Diego a (Di(a)) and the newly discovered antiserum to Di(b). Individuals with erythrocyte antigenic types Di(a+ b-, Di(a+ b+), and Di(a-b+) have been found, but the type Di(a-b-) has not been(More)
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