B. Suman Bharathi

Learn More
Biomedical systems involve complex interactions between diverse components. Problem solving in such systems requires insight, i.e. the capability to make non-obvious connections. In this paper, we present a game-based problem solving environment, where users can explore biological interactions with navigation on atomic to macroscopic scales, role-play, and(More)
Selenium exerts many, if not most, of its physiological functions as a selenocysteine moiety in proteins. Selenoproteins are involved in many biochemical processes including regulation of cellular redox state, calcium homeostasis, protein biosynthesis, and degradation. A neurodevelopmental syndrome called progressive cerebello-cortical atrophy (PCCA) is(More)
During development, axonal projections have a remarkable ability to innervate correct dendritic subcompartments of their target neurons and to form regular neuronal circuits. Altered axonal targeting with formation of synapses on inappropriate neurons may result in neurodevelopmental sequelae, leading to psychiatric disorders. Here we show that altering the(More)
Understanding and solving biomedical problems requires insight into the complex interactions between the components of biomedical systems by domain and non-domain experts. This is challenging because of the enormous amount of data and knowledge in this domain. Therefore, non-traditional educational tools have been developed such as a biological storytelling(More)
  • 1