B. Suman Bharathi

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OBJECTIVE Multiple sclerosis (MS) is considered a chronic inflammatory and demyelinating disease of the central nervous system. Evidence that axonal and neuronal pathology contributes to the disease is accumulating, however, the distribution of neuronal injury as well as the underlying mechanisms have not yet been fully clarified. Here, we investigated the(More)
Selenium exerts many, if not most, of its physiological functions as a selenocysteine moiety in proteins. Selenoproteins are involved in many biochemical processes including regulation of cellular redox state, calcium homeostasis, protein biosynthesis, and degradation. A neurodevelopmental syndrome called progressive cerebello-cortical atrophy (PCCA) is(More)
The recent release of the Intergovernmental Panel on Climate Change (IPCC) 4th Assessment Report (AR4) has generated significant media attention. Much has been said about the U.S. role in this report, which included significant support from the Department of Energy through the Scientific Discovery through Advanced Computing (SciDAC) and other Department of(More)
Biomedical systems involve complex interactions between diverse components. Problem solving in such systems requires insight, i.e. the capability to make non-obvious connections. In this paper, we present a game-based problem solving environment, where users can explore biological interactions with navigation on atomic to macroscopic scales, role-play, and(More)
During development, axonal projections have a remarkable ability to innervate correct dendritic subcompartments of their target neurons and to form regular neuronal circuits. Altered axonal targeting with formation of synapses on inappropriate neurons may result in neurodevelopmental sequelae, leading to psychiatric disorders. Here we show that altering the(More)
  • S Bharathi, A Ramesh, S Vivek, And J Vinoth Kumar
  • 2012
This paper presents a wearable obstacle avoidance system for blind people to navigate safely using cane and eyeglass methods. In cane method, an ultrasonic sensor is placed in cane which detects the obstacle in the ground level. In eyeglass method, an ultrasonic sensor is used which detects obstacle above the head up to certain angle. The information(More)
  • K Arulmozhi, S Arumuga Perumal, K Kannan, S Bharathi
  • 2010
Digital Image enhancement provides a multitude of choices for improving the visual quality of radiographic images. When the details of radiographic image are lost due to various reasons, image enhancement has been applied. Many algorithms have been proposed for image enhancement in the past decade. Contrast improvement algorithms are used to enhance image(More)
Understanding and solving biomedical problems requires insight into the complex interactions between the components of biomedical systems by domain and non-domain experts. This is challenging because of the enormous amount of data and knowledge in this domain. Therefore, non-traditional educational tools have been developed such as a biological storytelling(More)
The values of Standardized Distal Motor Latency (SDML) of Median, Ulnar and Common Peroneal nerves and the peak to peak amplitude of Evoked Muscle Action Potentials (EMAP) of the small muscles of the limbs were studied in 50 normal subjects. The SDML values showed significant sex difference, whereas no sex difference was observed in the amplitude of the(More)