B. Strindberg

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After oral administration of14C-labelled emepronium (150 mg) to two subjects, 1.8 and 3.9% of the radioactivity were recovered from the urine within 24 h, of which 50 and 56% respectively, were excreted during the first 6 h. 23 to 35% of the radioactivity in the urine consisted of emepronium metabolites. 25 mg of the cold compound was injected i.m. in 4(More)
Cisobitan, an organosilicon compound with estrogenic and antigonadotropic properties has been evaluated clinically in comparison with an estrogen preparation. In a multicenter study a total of 140 patients with well and moderately well differentiated prostatic cancer were randomly allocated to treatment with Cisobitan or Estradurin/Etivex, 70 to each group.(More)
192-rhGH (Somatrem) with ECPC of 285-1400 (SI), 170-30 (SII)and <10 (SIII)/ng/vial was used in 3 studies in GHDP not previously (“new”) or previously (“old”) treated with pit-hGH. In 8 “old” patients (duration 1 month (m)), glucose and insulin responses in the OGTT, insulin binding in erythrocytes and somatomedin activity (SMA) were similar on pit-hGH or(More)
Patients with poorly differentiated prostatic carcinoma and skeletal metastases were randomized to treatment with 2.6-cis-diphenylhexamethylcyclotetrasiloxane (2.6-cis) and estramustine-17-phosphate (estramustine). Parallel with the clinical study a group of non-randomized patients were treated with 2.6-cis. Cytological regression of the tumor could be(More)
Three studies of human growth hormone (hGH) in hGH deficiency were initiated. In the first of these, adolescent patients were switched from pituitary hGH to somatrem (SI preparation) for 1 month. No significant differences were noted in any of the clinical parameters measured during treatment with either preparation. In the second study, nine patients (six(More)
The effect of growth hormone (GH) and somatomedin (SM) on the recovery of sheep red blood cell (SRBC) receptor in trypsinized human T-lymphocytes was studied either with the use of sera from patients with acromegaly or pituitary dwarfism or after the addition of exogenous GH, SM or thymosin to human sera. It was found that GH does not show any effect on the(More)