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Methomyl, or S-methyl-N [(methylcarbamoyl)oxy] thioacetimidate, a common insecticide, has been found to be a specific poison of mitochondria of corn with ‘Texas’ cytoplasm. Its hydrolysis under very mild acidic conditions affords thiomethyl methylthiosulphonate, which strongly inhibits the activity of ‘CmST’ and ‘N’ mitochondria of corn.
A series of 24 carbamates was obtained by structural modification of methomyl, or S-methyl-N[(methylcarbamoyl)oxy]thioacetimidate, an insecticide. The biological activity of this series and that of 7 other compounds was studied by measuring root growth of germinating corn plants with Texas and normal cytoplasm. The contribution of each substitution to(More)
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