The antiepileptic effect of lamotrigine (Lamictal) was assessed in a double-blind, placebo-controlled, crossover trial in 56 adult patients with refractory partial seizures. Lamotrigine or placebo was added to the patients' existing antiepileptic drugs (AEDs). The dose of lamotrigine varied from 75 to 400 mg daily. Thirty-eight patients completed the trial… (More)
A single-dose study of the beta-carboline, ZK 95962, on photosensitive generalized paroxysmal activity in the EEG was conducted in 6 patients with primary generalized epilepsy. Four of the patients were newly diagnosed and did not receive any antiepileptic drug or other medication during the study. Two were receiving current therapy with carbamazepine. A… (More)
The probe microphone devised by Lauridsen & Günthersen (1981) was tested in a clinical situation, and the results were compared with those obtained with a miniature electret microphone place in the ear canal (cf. Harford, 1980), and also with those obtained with the eardrum microphone on the acoustic manikin KEMAR. Good agreement was found between all three… (More)
The ganglion Gasseri and the brainstem were examined in three old patients with herpes zoster without predisposing diseases with special reference to the mesencephalic trigeminal nucleus. The primary lesions in the semilunar ganglion vary with the length of the course. Secondary changes in the brainstem were as expected from pons to the second cervical… (More)
In a prospective investigation concerning 50 consecutive patients suffering from complex partial epilepsy who all had a normal CT investigation pathological findings were recognized in 80% using MRI. The MRI examination included volume estimation of the hippocampus. The volume estimations were compared to a reference material. In 24% a focal pathology was… (More)
Earmoulds according to the horn principles often lack the necessary space for a vent parallel to the sound canal. The present paper shows that a 2 mm vent ending in the sound canal itself near the tip of the earmould does not affect the frequency characteristics of the hearing aid measured at the eardrum.