B Nunes Cardozo

Learn More
The mammalian circadian pacemaker of the suprachiasmatic nucleus (SCN) is entrained to the environmental light-dark cycle via a retinal projection, the retinohypothalamic tract (RHT). Several studies suggest that an excitatory amino acid, possibly glutamate, is involved in photic entrainment. However, it has not yet been established whether glutamate is a(More)
The expression and distribution of AMPA, kainate and NMDA glutamate receptor subunits was studied in the goldfish retina. For the immunocytochemical localization of the AMPA receptor antisera against GluR2, GluR2/3 and GluR4 were used, and for in situ hybridization rat specific probes for GluR1 and GluR2 and goldfish specific probes for GluR3 and GluR4 were(More)
The ultrastructural organization of the pretecto-olivary projection neurons within the nucleus of the optic tract and dorsal terminal accessory optic nucleus of rabbits was studied by using anti-GABA immunolabelling and retrograde transport of WGA-HRP. GABA-like immunoreactivity was determined with a postembedding colloidal gold technique. WGA-HRP was(More)
In this study the medial terminal nucleus (MTN) projection to the nucleus of the optic tract (NOT) was investigated in pigmented rats at the light and electron microscopical levels with a new combination of techniques. MTN terminals were anterogradely labeled with Phaseolus vulgaris-leucoagglutinin (PHA-L). Preembedding immunocytochemistry, followed by gold(More)
A combined Golgi-electron microscope method was used to study the ultrastructural maturation of synapses on identified pyramidal and multipolar non-pyramidal neurons in the visual cortex of young and adult rabbits. In samples of 10 (time of eye opening), 14, 20 day old and 7 month old animals, fully impregnated pyramidal neurons within the layers II-V and(More)
The visual cortex of 20 day old rats and rabbits has been considered as mature on the basis of the observations that the dendritic arborization and the overall synaptic population have almost reached their adult stage in these animals. In the present study we have investigated the visual cortex of 20 day and 7 month old (adult) rabbits in order to determine(More)
Immunodetection techniques are dependent on enzyme-protein conjugates for the visualisation of antigen-antibody complexes. One of the most widely used is the avidin-biotin-peroxidase complex (ABC) method. The present study demonstrates that direct treatment of goldfish and salamander retinal sections with ABC, followed by an incubation with the chromogenic(More)
Both the nucleus of the optic tract (NOT) and the superior colliculus (SC) are thought to play important roles in the regulation of eye movements. The superior colliculus contributes to visual orientation and saccades, and the nucleus of the optic tract contributes to the detection of slow movements of the visual surround. Recently, a GABAergic projection(More)
The reciprocal connection between the nucleus of the optic tract and the superior colliculus has been described for several species. In both nuclei GABA is an important transmitter and recently it has been shown that GABA plays a significant role in this connection. To investigate this reciprocal connection at the ultrastructural level in the rabbit,(More)
  • 1