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Rapidly spreading infectious diseases are a serious risk to public health. The dynamics and the factors causing outbreaks of these diseases can be better understood using mathematical models, which are fit to data. Here we investigate the dynamics of a Hepatitis E outbreak in the Kitgum region of northern Uganda during 2007 to 2009. First, we use the data(More)
Nodding syndrome has affected and led to the deaths of children between the ages of 5 and 15 in Northern Uganda since 2009. There is no reliable explanation of the disease, and currently the only treatment is through a nutritional programme of vitamins, combined with medication to prevent symptoms. In the absence of a proper medical treatment, we develop a(More)
Numerous studies have been carried out on within-host Plasmodium falciparum malaria with varying results. Some studies have suggested over estimation of parasite growth within an infected host while others stated that evolution of parasitaemia seems to be quelled by parasite load. Various mathematical models have been designed to understand the dynamics of(More)
In this paper, a co-infection of malaria and visceral helminthiasis with immune stimulation and impairment is studied. We have assumed that an individual gets malaria infection during invasion by helminths larvae. In absence of immune response, our results show that the antigens invade the blood system if the rate of red cell rupture per invading merozoite(More)
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