B N Belintsev

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One of the most universal events in morphogenesis is the formation of domains of morphologically polarized cells in the initially homogeneous epithelial sheets. We investigate the possibility of considering this process as a phenomenon of self-organization which is based upon the following experimentally proven mechanochemical cell properties: (1) a(More)
It is well known that in embryonic tissues at the key stages of morphogenesis there arise stable, stage--specific tension fields. These fields occur due to particular pattern of morphologically polarized cells. Some basic properties have been understood previously. 1. Morphologically polarized and isotropic shapes correspond to the alternative stable states(More)
A new theoretical model is presented which describes dynamics of interaction between the plasmic membrane, cell cortex and cytoplasmic liquid. Analysis of the equation system describing this interaction has shown that besides the uniform solution (corresponding to a flat cell surface) there exists the stable autowave solution (corresponding to standing or(More)
An attempt to estimate the relative contributions of twisting and bending to the free energy of superhelix formation from the relaxed DNA is undertaken. The extent of teritiary ordering (number of DNA axis turns tau) and that of secondary ordering (duplex twist angle beta) have been taken as thermodynamical parameters, which characterize the state of the(More)
On the basis of published measurements of the melting transitions of synthetic polydeoxyribonucleotides with known sequences we have determined the parameters of the interplane (stacking) interactions of base pairs in DNA over the range of ionic strengths from 0.01 to 0.1 M Na+. We found that deviations of the stacking-interaction energy from the mean value(More)
The results of general investigation presented at the previous paper [9] are applied to interpreting the spatial ordering upon positional differentiation at the development of multicellular organisms. The very form of local dynamics is not specified for the lack of sufficient information about the mechanisms of biosynthesis regulation in multicellular(More)
The emergence of the developmental axis within the early aggregate Dictyostelium discoideum is analyzed. Macroscopic parameters of physical continuum such as hydrostatic pressure and surface tension are applied to the cell mass. Cell chemotaxis, differential rate of attractant production by the prestalk and prespore cells and attractant diffusion are shown(More)
Mechanism of spontaneous initiation of bendings in plane cellular layers is considered. The theoretical consideration is underlied by an experimentally substantiated hypothesis concerning local activation of cellular divisions in the places of future protrudings. The disturbance of the plane form of the cell layer is the result of Euler instability locally(More)