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PURPOSE To assess interim safety and tolerability of a 10-patient, Phase II pilot study using bevacizumab (BV) in combination with temozolomide (TMZ) and regional radiation therapy (RT) in the up-front treatment of patients with newly diagnosed glioblastoma. METHODS AND MATERIALS All patients received standard external beam regional RT of 60.0 Gy in 30(More)
Normal breast sensation was objectively quantitated with a biothesiometer, Semmes-Weinstein monofilaments, and two-point discrimination in 10 patients. Ten patients, 2 to 7 years after pedicled transverse rectus abdominis musculocutaneous flap (TRAM) breast reconstruction, were tested in a similar manner. The majority of these patients were found to have(More)
We report on four patients with partial and full thickness burns following autogenous tissue breast reconstruction. Three burns were confined to the flap and one burn involved the flap and rim of adjacent skin. Heat sources included a heating pad (n = 3) and sunlight through a bathing suit (n = 1). The injuries occurred from 6 days to 4 years following the(More)
This paper presents a new structure-preserving method of sampling self-similar traffic with direct applications to network monitoring and resource provisioning. Predicting the bandwidth required by upcoming traffic plays a key role for providing an efficient and intelligent resource provisioning, especially in the context of IP over WDM. To achieve this, we(More)
One-third of a group of 18 patients with hemifacial microsomia demonstrated velopharyngeal insufficiency of a significant degree. The ones with velopharyngeal insufficiency tended to have more severe soft tissue and skeletal deformities of the maxillary-malar complex, associated with a total unilateral palatal paralysis. Cinefluoroscopy was not helpful in(More)
For the past 2 decades there has been a definite trend among pelvic surgeons to immediately reconstruct the large defects created by deforming radical cancer surgery in the female pelvis and perineum. Extensive en bloc removal of more tissue has enhanced the probabilities of increased 5-year survival. At the same time, however, the quality of life following(More)