• Publications
  • Influence
An active foamy virus integrase is required for virus replication.
Foamy viruses (FVs) make use of a replication strategy which is unique among retroviruses and shows analogies to hepadnaviruses. The presence of an integrase (IN) and obligate provirus integrationExpand
  • 41
  • 3
Foamy virus reverse transcriptase is expressed independently from the Gag protein.
In the foamy virus (FV) subgroup of retroviruses the pol genes are located in the +1 reading frame relative to the gag genes and possess potential ATG initiation codons in their 5' regions. ThisExpand
  • 110
  • 2
  • PDF
Expression of human foamy virus reverse transcriptase involves a spliced pol mRNA.
In human foamy virus (HFV) the reverse transcriptase is expressed independently of the Gag protein as a 127-kDa Pol precursor molecule. Evaluating the mechanism of Pol expression we identified aExpand
  • 53
  • 1