B. M. Rohini Fernandopulle

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OBJECTIVES Acute paracetamol poisoning is an emerging problem in Sri Lanka. Management guidelines recommend ingested dose and serum paracetamol concentrations to assess the risk. Our aim was to determine the usefulness of the patient's history of an ingested dose of >150 mg/kg and paracetamol concentration obtained by a simple colorimetric method to assess(More)
OBJECTIVE To evaluate the risk of fulminant hepatic failure in relation to paracetamol overuse with therapeutic intent in febrile children. METHODS It was a case control study. Paracetamol ingestion for the current febrile illness was compared between 25 cases of fulminant hepatic failure and 33 hospital age matched controls. RESULTS Supra-therapeutic(More)
OBJECTIVES To compare the management of acute paracetamol poisoning with the best evidence available, and to determine the effect of plasma paracetamol level estimation on the management. DESIGN Descriptive study with an intervention. SETTING Medical wards of the National Hospital of Sri Lanka, Colombo. PATIENTS Patients admitted with a history of(More)
BACKGROUND No pricing formula has been implemented from November 2002 to date in Sri Lanka. Therefore, we initiated a study in 2003 to determine the prices, availability and affordability of medicines in the private sector of Sri Lanka in the absence of a price control. MATERIALS AND METHODS The World Health Organization/Health Action International(More)
This study analyses retrospectively some of the risks associated with the use of WHO-multidrug therapy (MDT) in Sri Lanka. Case records of 3,333 new cases of leprosy attending the Central Leprosy Clinic in Colombo during 1991-1995, were analysed for adverse drug reactions involving the liver and blood. There were 81 reports of suspected hepatic or(More)
OBJECTIVES To find out whether iodised edible salt available for sale to the public is iodised, iodination is within the Sri Lanka Standards Institute (SLSI) specifications and the labelling is accurate. DESIGN 38 packets of iodised salt from 11 different brands were randomly purchased from retail outlets in 5 different areas and analysed for iodine(More)
OBJECTIVES Antibacterial resistance (ABR) is a public threat. Sri Lanka is a country with limited surveillance of ABR in the community. The WHO methodology was adapted to identify ABR in outpatient settings (nonhospitalised patients) and its link to consumption of antibiotics. METHODS It was a cross-sectional descriptive community based study to collect(More)