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PURPOSE Cell cycle dysregulation resulting in expression of antiapoptotic genes and uncontrolled proliferation is a feature of undifferentiated nasopharyngeal carcinoma. The pharmacodynamic effects of seliciclib, a cyclin-dependent kinase (CDK) inhibitor, were studied in patients with nasopharyngeal carcinoma. EXPERIMENTAL DESIGN Patients with(More)
In response to ever-increasing demand for computing power, a high-end server microprocessor with two silicon die in a multi-chip module (MCM) package was planned. For the MCM microprocessor to work optimally, the two large silicon die (each with more than 10,000 C4 bumps) need to communicate efficiently with each other. This requires many copper routing(More)
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