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Fifty consecutive patients (aged 19–77 years, median 56 years) with primary cerebral diseases and the clinical signs of absent cortical and brainstem function were subjected to electroencephalography (EEG), brainstem acoustic evoked potentials (BAEP), extracranial Doppler ultrasonography (ECD) and arterial digital subtraction angiography (DSA). In the(More)
It is well known that transcranial stimulation, delivered during sustained muscle contraction, evokes a temporary suppression of motor activity (silent period). The aim of the present study was to further analyze this inhibition in 20 healthy subjects and in 10 patients with previous stroke. Transcranial magnetic stimulation was performed at the vertex,(More)
  • B Kukowski
  • Electromyography and clinical neurophysiology
  • 1993
Analysis of motor evoked potentials (MEP) after magnetic brain stimulation is often restricted to measurement of latency and amplitude. In the present study, which was conducted in healthy controls and in patients with multiple sclerosis (MS), the additional value of MEP duration and configuration was evaluated. Recordings were made from distal muscles of(More)
Neuromyotonia is a rare condition of peripheral nerve dysfunction characterized by the signs of motor nerve hyperactivity, namely, myokymia, fasciculations, and muscular stiffness. Relaxation of voluntary muscle contraction is delayed, and fluid movements are impaired to a variable degree. Signs of sensory involvement are less frequent. Usually, therapy(More)
In muscles with sustained voluntary contraction, EMG activity is transiently inhibited after transcranial magnetic stimulation. We recorded this postexcitatory silent period (SP) at 1.5 times individual stimulus threshold level from the first dorsal interosseus muscle in 65 neurologic patients aged 11 to 80 years. When compared with 20 healthy volunteers(More)
  • B Kukowski
  • Archives of physical medicine and rehabilitation
  • 1993
A 25-year-old semi-professional dancer developed painless, isolated weakness of external rotation of the right arm. Physical examination was otherwise normal. Electromyography showed selective partial denervation of the infraspinatus muscle. Stimulation of the suprascapular nerve at Erb's point demonstrated delayed conduction to the infraspinatus muscle.(More)
High intensity transient signals (HITS) have been identified ultrasonically in patients with extracranial vascular or cardiac disease and are suggestive of microembolic material. We studied the prevalence of these signals in 60 patients with increased risk for cardioembolic stroke and in a control group of 20 subjects. Patient groups (n = 20) were(More)
Four days after implantation of a biventricular assist device (Berlin heart) the 39-year-old patient showed a sudden loss of vigilance and tetraplegia. Clinical skills and neurophysiological states indicated a serious lesion of the brain stem. After a test application of Physostigmine 2 days later, the neurological deficits improved dramatically. The case(More)
  • B Kukowski
  • Electroencephalography and clinical…
  • 1991
In a patient with adrenoleukodystrophy (ALD), prolonged conduction times along the corticospinal tract and afferent sensory pathways were demonstrated using magnetic transcranial brain stimulation and multimodality evoked potentials, respectively. On investigation of two healthy family members (one an obligate carrier), slight latency increases in evoked(More)
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