B Jayasiri C Perera

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OBJECTIVE To establish efficacy and safety of deferiprone. DESIGN Prospective study. SETTING The Lady Ridgeway Hospital for Children, Colombo. PATIENTS Transfusion-dependent children in the age group 1 to 15 years. INTERVENTION Patients were given 75 mg/kg/day of deferiprone orally in divided doses. MEASUREMENTS Efficacy of deferiprone therapy was(More)
Eighty six children with troublesome wheezing were studied, in a semiprospective clinical trial with the patients acting as their own controls, to assess the efficacy and cost effectiveness of inhaled steroids. Improvement in school attendance, hospitalisations, breakthrough wheezing, and acute severe attacks were used to assess clinical efficacy.(More)
A hospital-based descriptive recall study was conducted to assess the relationship, if any, between breastfeeding practices and morbidity from respiratory and diarrhoeal diseases in infants. A total of 343 infants (285 admitted patients and 58 controls) were recruited. Clinical and sociodemographic data and details regarding breastfeeding practices, timing(More)
OBJECTIVE To determine the efficacy and safety of deferiprone. DESIGN Prospective study. SETTING 5 paediatric medical units at the Lady Ridgeway Hospital for Children (LRHC), Colombo. PATIENTS Transfusion-dependent iron overloaded children in the age group 2 to 15 years. INTERVENTION Patients were given a total daily dose of 75 mg/kg of deferiprone(More)
OBJECTIVES 1. To assess the clinical efficacy of drug delivery using paper spacer devices coupled to metered dose inhalers (MDI). 2. To compare the effectiveness of paper spacers with the standard volumatic spacer. DESIGN Randomised double-blind placebo controlled clinical trial. SETTING Asthma clinic of a family practice at Kalutara. PATIENTS 134(More)