B Jayasiri C Perera

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OBJECTIVE To determine the efficacy and safety of deferiprone. DESIGN Prospective study. SETTING 5 paediatric medical units at the Lady Ridgeway Hospital for Children (LRHC), Colombo. PATIENTS Transfusion-dependent iron overloaded children in the age group 2 to 15 years. INTERVENTION Patients were given a total daily dose of 75 mg/kg of deferiprone(More)
A hospital-based descriptive recall study was conducted to assess the relationship, if any, between breastfeeding practices and morbidity from respiratory and diarrhoeal diseases in infants. A total of 343 infants (285 admitted patients and 58 controls) were recruited. Clinical and sociodemographic data and details regarding breastfeeding practices, timing(More)
Eighty six children with troublesome wheezing were studied, in a semiprospective clinical trial with the patients acting as their own controls, to assess the efficacy and cost effectiveness of inhaled steroids. Improvement in school attendance, hospitalisations, breakthrough wheezing, and acute severe attacks were used to assess clinical efficacy.(More)
OBJECTIVE Although inhaled corticosteroids are useful and effective in the prophylaxis of childhood asthma, there is a dearth of information regarding the duration of treatment. The present study was undertaken to assess the possibility of successful withdrawal of inhaled corticosteroids in childhood asthma following good control of the disease. (More)
A case of hyperhemolysis in a 2-year-old boy with beta thalassemia major was noted. After several transfusions, he developed hyperhemolysis with a positive (C3d only) direct antiglobulin test (DAT) and no clinically significant RBC allo- or auto-antibodies. (There was a weak cold antibody, showing a narrow thermal range). Because there was no significant(More)
OBJECTIVE To establish efficacy and safety of deferiprone. DESIGN Prospective study. SETTING The Lady Ridgeway Hospital for Children, Colombo. PATIENTS Transfusion-dependent children in the age group 1 to 15 years. INTERVENTION Patients were given 75 mg/kg/day of deferiprone orally in divided doses. MEASUREMENTS Efficacy of deferiprone therapy was(More)
OBJECTIVES To identify the causative bacteria in childhood acute respiratory infections (ARI) and to determine the usefulness of pus cell counts in differentiating between pathogenic and commensal bacteria, cultured from nasopharyngeal aspirates. DESIGN Case control prospective study. SETTING Outpatients' department and the paediatric unit at General(More)