Recent neurophysiological findings have demonstrated that abstinent chronic alcoholics manifest deficits in event-related brain potentials. To explore possible biological antecedents of alcoholism… (More)
We have previously found that the P3 component of the event-related potential (ERP) is reduced in alcoholics in visual target-selection paradigms. P3 voltage depends on the "subjective significance"… (More)
The latencies of the N2 component of the ERP and reaction time were manipulated in abstinent alcoholics and controls. The experimental design consisted of visual stimuli that differed in difficulty… (More)
An alcohol withdrawal syndrome characterized by the successive appearance of hyperactivity and tremors, muscle spasticity and, in some animals, generalized convulsions was induced in rats. It was… (More)