B Gleissner

Learn More
BACKGROUND Cytologic evaluation of CSF does not consistently detect malignant cells in patients with primary CNS lymphoma (PCNSL). The potentially more sensitive molecular assessment of monoclonality has not been shown in CSF samples. METHODS The authors studied nested PCR of the complementary determining region III (CDR III) on 76 CSF specimens of(More)
The oculomotor and manual motor systems were studied in a two-segment movement task in a group of patients with Parkinson's disease and in age matched normal controls. In order to avoid reflexive motor movements the selection of the correct motor sequence was derived from the interpretation of symbolic (coloured) cues. The latencies and dynamics of eye and(More)
The frequency of central nervous system (CNS) dissemination in non-Hodgkin's lymphoma (NHL) varies and is dependent on NHL histology. More than 50% of patients with CNS involvement have advanced and progressive systemic disease. While CNS involvement at initial diagnosis may be treated curatively, treatment of CNS involvement in systemic relapsing or(More)
eoplastic meningitis arises in cancer patients through the deposition of malignant cells in the leptomeninges and subarachnoid space. Its incidence seems to be rising because of improvements in the systemic treatment of malignant neoplasms of the hemato-poietic system and of other types of cancer. To provide an objective basis for therapeutic(More)
  • 1