The curve of a reduction in plasma concentration of the indicator substance creatinine for a period of 120 to 240 min was investigated after single intravenous administration of creatinine in a dose… (More)
Osmotic diuresis (15% mannitol, 4.5 ml/hr) was in duced in anesthetized rats. At the end of each of 10 consecutive 10-min clearance periods the following parameters were determined: diuresis, sodium,… (More)
Experiments were carried out on male white rats of Wistar strain, placed in metabolic cages in a room with artificial light and dark at 12-hour periods. Furosemide in a dose of 4 mg/kg was used… (More)