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Ingrowth of fibrovascular tissue from the woundbed into collagen-based dermal substitutes and survival of cultured epithelium after transplantation may be enhanced by attachment of heparin binding growth factor 2 (HBGF2) and epidermal growth factor (EGF) to collagen. Biotinylation of collagen and the growth factors allows immobilization of HBGF2 and EGF by(More)
Fibrous dysplasia of the cervical spine is rare. No prior reports have discussed odontoid fractures in the setting of fibrous dysplasia. We describe a 26-year-old man who suffered a traumatic odontoid fracture in an area of preexisting fibrous dysplasia. The patient was treated conservatively in a sterno-occipito-mandibular immobilizer brace with a good(More)
Craniofacial fibrous dysplasia, a skeletal disorder most often affecting the mandible or maxilla, can cause a variety of complications. Nasal obstruction secondary to this unusual disorder presents a diagnostic and therapeutic challenge. The nasal obstruction in this case is due to expansion of fibrous lesions in adjacent bones as well as direct involvement(More)
Bloodless surgical procedures on the extremities are achieved by application of a pneumatic tourniquet. The ischemia produced has deleterious effects on nerve and muscle function. It has been suggested that temporary interruption of ischemia by a reperfusion interval can prevent muscle and nerve injury. We investigated the muscle and nerve response to 3(More)
presented at the 15th Annual Meeting of the Society for Biomaterials, April 28-May 2,1989. Supported by NIH Grant GM35068. "To whom correspondence should be addressed at Department of Surgery, ML 558, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267-0558. Journal of Biomedical Materials Research, Vol. 26, 547-553(More)
Microvascular free-tissue transfer is often employed to achieve limb salvage in traumatic leg wounds. Previous experience has shown that one cause of flap failure is placement of the microvascular anastomoses within the zone of injury and subsequent thrombosis. This observation has prompted surgeons to perform anastomoses on the proximal uninjured recipient(More)
Fibrous dysplasia of bone is a disorder of unknown etiology in which skeletal aberrations constitute the cardinal feature. The condition is often monostotic but may be polyostotic. The disorder may be accompanied by extraskeletal manifestations, such as abnormal cutaneous pigmentation and endocrinopathies, most commonly precocious puberty. Surgical therapy(More)
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