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To investigate the role of IL-6 in systemic lupus erythematosus (SLE), we selectively inhibited IL-6 in lupus-prone NZB/NZW F1(B/W) mice by chronic administration of a rat mAb to mouse IL-6.… (More)
Proteins of extracellular matrix undergo over time multiple reactions with glucose to form advanced glycosylation endproducts (AGEs) which are highly active in protein crosslinking, and have been… (More)
Objective To observe the effect of hypercholesterolemia on the expression of VEGF in endothelial cells and the role of simvastatin.Methods Cultured endothelial cells were treated with different… (More)
Cancer immunotherapy is a major branch of biological therapy that utilises living cells and their products. Advances in molecular biology and immunology have led to the development of novel… (More)