B. -Ch. Burckhardt

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The mechanism of bicarbonate transport across the peritubular cell membrane was investigated in rat kidney proximal tubules in situ by measuring cell pH and cell Na+ activity in response to sudden reduction of peritubular Na+ and/or HCO 3 − . The following observations were made: 1. sudden peritubular reduction of either ion concentration produced the same(More)
Background Infections by multidrug-resistant Pseudomonas aeruginosa (MDRPa) are an important cause of morbidity and mortality in patients after allogeneic hematopoietic stem cell transplantation (HSCT). Humid environments can serve as a reservoir and source of infection by this pathogen. To minimize the risk of infection from these reservoirs, we performed(More)
A major t r a n s p o r t f u n c t i o n o f mammalian p rox ima l t u b u l e s i s the a b s o r p t i o n of b i c a r b o n a t e . We know today t h a t HCO~ is taken up i n t o the c e l l s t h rough s e c r e t i o n of H + i n t o the t u b u l a r lumen ( m o s t l y in e l e c t r o n e u t r a l exchange f o r Na + i o n s ) . H + ions r eac t(More)
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