B. B. Panigrahi

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The in vitro response of the mouse fibroblast cell line 3T3 on the surface of ultrafine grained titanium [produced by a severe plastic deformation (SPD) process] has been studied in this work. SPD Ti showed much higher strength than the coarse grained Ti and equivalent to that of Ti-6Al-4V alloy. Better cell proliferation was observed on SPD Ti compared to(More)
The present investigation is concerned with formulation and evaluation of mucoadhesive buccal tablets containing antihypertensive drug, Timolol maleate to circumvent the first pass effect and to improve its bioavailability with reduction in dosing frequency and dose related side effects. The tablets were prepared by direct compression method. Eight(More)
This work attempts to understand the in vitro biocompatibility of ultrafine grained titanium prepared by the ECAP route. The results obtained from the mouse fibroblast cell line 3T3 showed a better cell adherence and cell proliferation on ECAP titanium specimen compared to the coarse grain Grade-2 Ti and Ti6Al4V alloy. This could be attributed to the(More)
Acyclovir microcapsules with a coat consisting of alginate and a mucoadhesive polymer such as carbopol 934P and hydroxypropyl methyl cellulose E 15 V were prepared by an ionotropic gelation technique, where gelation was achieved with oppositely charged counter ions to form microcapsules. The microcapsule prepared were found to be spherical to near spherical(More)
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