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Chronic beryllium disease is an occupational lung disease that begins as a cell-mediated immune response to beryllium. Although respiratory and engineering controls have significantly decreased occupational beryllium exposures over the last decade, the rate of beryllium sensitization has not declined. We hypothesized that skin exposure to beryllium(More)
  • B A Rich
  • 1998
This article considers 2 major critiques of advance directives and offers a defense to each of them. The 1st critique is philosophical in nature and maintains that the moral authority of an advance directive is undercut by a failure of personal identity to survive the loss of decisional capacity. The response in this article is that this critique relies on(More)
Previously, we demonstrated that restraint stress applied before chemical sensitization modulates allergic contact dermatitis (ACD) differently than restraint applied before challenge. In this study, we asked if these dichotomous restraint-induced changes reflect modulation of the cutaneous microenvironment or changes in development of antigen-specific(More)
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