Bérengère Mitel

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Lipid hydroperoxides have been reported to regulate cell function and eicosanoid formation. The aim of the present study was to determine the effect of 12(S)-hydroperoxy-eicosatetraenoic acid [12(S)-HPETE], the platelet 12-lipoxygenase-derived hydroperoxide of arachidonic acid (AA), on the availability of nonesterified AA, which represents a rate-limiting(More)
Considerable interest exists concerning the role played by lipid peroxides in cell damage and in the development of cardiovascular diseases. Indeed, an exacerbated platelet activation, as observed in aging, was associated with an increased overall lipid peroxidation and an increased peroxidation of arachidonic acid (AA). The platelet antioxidant defenses(More)
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