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UNLABELLED In patients with chronic hepatitis C (CHC), cirrhosis is associated with age, gender, diabetes, alcohol abuse, and coinfection with human immunodeficiency virus (HIV) or hepatitis B virus (HBV). The effect of these factors on the outcome of cirrhosis is unknown. This study in CHC patients with cirrhosis aimed to assess the influence of these(More)
OBJECTIVES To evaluate the risk of very preterm birth (22-32 weeks of gestation) associated with previous induced abortion according to the complications leading to very preterm delivery in singletons. DESIGN Multicentre, case-control study (the French EPIPAGE study). SETTING Regionally defined population of births in France. SAMPLE The sample(More)
BACKGROUND The aim was to evaluate the value of magnetic resonance imaging (MRI) findings in Crohn's disease (CD) in correlation with pathological inflammatory score using surgical pathology analysis as a reference method. METHODS CD patients who were to undergo bowel resection surgery underwent MR enterography before surgery. The CD pathological(More)
AIM The aim of this study was to assess the independent role of cerebral lesions on ultrasound scan, and several other neonatal and obstetric factors, as potential predictors of cerebral palsy (CP) in a large population-based cohort of very preterm infants. METHOD As part of EPIPAGE, a population-based prospective cohort study, perinatal data and outcome(More)
OBJECTIVES We compared the frequency of behavioral problems in very preterm and term children at 5 years of age. We hypothesized that behavioral problems would be associated with cognitive impairment and environmental factors and that differences between the 2 groups would be reduced but persist after adjusting for cognitive performance and environmental(More)
OBJECTIVE To estimate the prevalence of cerebral palsy at 2 years of age among children born very preterm, according to gestational age, infant gender, plurality, and neonatal cranial ultrasound abnormalities. METHODS All infants born between 22 and 32 weeks of gestation in 9 regions of France in 1997 were included in this prospective, population-based,(More)
OBJECTIVE To assess the relationship between cigarette smoking during pregnancy and very preterm births, according to the main mechanisms of preterm birth. DESIGN Case-control study (the French Epipage study). SETTING Regionally defined population of births in France. POPULATION Eight hundred and sixty-four very preterm live-born singletons (between(More)
OBJECTIVES Our goal was to compare the prevalence of behavioral problems between very preterm children and term children at 3 years of age and examine the factors associated with behavioral problems in very preterm children. METHODS We conducted a prospective population-based cohort study: the EPIPAGE (Etude Epidémiologique sur les Petits Ages(More)
BACKGROUND It is not yet known whether the risk of developing atopic dermatitis (AD) is influenced by preterm birth. Moreover, AD risk has not been assessed in a large sample of extremely preterm infants (< 29 weeks' gestation). OBJECTIVES To determine whether the risk of AD is influenced by preterm birth. METHODS We investigated the relationship(More)
OBJECTIVES To investigate school difficulties, special care and behavioral problems in 8 year-old very preterm (VPT) children. PATIENT AND METHODS Longitudinal population-based cohort in nine regions of France of VPT children and a reference group born at 39-40 weeks of gestation (WG). The main outcome measures were information about school, special care(More)