Béatrice Cochener

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The detection of microaneurysms in digital color fundus photographs is a critical first step in automated screening for diabetic retinopathy (DR), a common complication of diabetes. To accomplish this detection numerous methods have been published in the past but none of these was compared with each other on the same data. In this work we present the(More)
BACKGROUND The purpose of this study was to record the visual outcomes of patients treated by six surgeons after implantation of a trifocal lens. METHODS The setting for this study comprised six ophthalmology units and eye clinics in Belgium and France, with a coordinating center in France, and data management and statistical analysis in France and(More)
In this paper, we propose an automatic method to detect microaneurysms in retina photographs. Microaneurysms are the most frequent and usually the first lesions to appear as a consequence of diabetic retinopathy. So, their detection is necessary for both screening the pathology and follow up (progression measurement). Automating this task, which is(More)
We present in this paper a novel way to adapt a multidimensional wavelet filter bank, based on the nonseparable lifting scheme framework, to any specific problem. It allows the design of filter banks with a desired number of degrees of freedom, while controlling the number of vanishing moments of the primal wavelet (\mathtilde <i>N¿</i> moments) and of the(More)
We propose in this article a content-based image retrieval (CBIR) method for diagnosis aid in medical fields. In the proposed system, images are indexed in a generic fashion, without extracting domain-specific features: a signature is built for each image from its wavelet transform. These image signatures characterize the distribution of wavelet(More)
PURPOSE To evaluate the potential of intrastromal corneal ring technology (Intacs, KeraVision) to correct keratoconus without central corneal scarring. SETTING Department of Ophthalmology, Brest University Hospital, Brest, France. METHODS In this prospective, noncomparative, interventional case series, Intacs segments were implanted in 10 keratoconic(More)
A novel content-based heterogeneous information retrieval framework, particularly well suited to browse medical databases and support new generation computer aided diagnosis (CADx) systems, is presented in this paper. It was designed to retrieve possibly incomplete documents, consisting of several images and semantic information, from a database; more(More)
OBJECTIVE To determine the accuracy of salivary gland ultrasonography (SGUS) for diagnosing primary Sjögren's syndrome (SS) and to suggest modifications of the American-European Consensus Group (AECG) classification criteria. METHODS We conducted a cross-sectional study in a prospective cohort of patients with suspected primary SS that was established(More)
PURPOSE To compare a treatment containing carboxymethylcellulose (CMC) and the osmoprotective (OsPr) compatible osmolytes erythritol, L-carnitine, and glycerin (OsPr-CMC) with a standard sodium hyaluronate (Na-HY) formulation in patients with dry eye disease. METHODS This was a 3-month, phase III, noninferiority study. Patients were randomized 1:1 to(More)
A novel multiple-instance learning framework, for automated image classification, is presented in this paper. Given reference images marked by clinicians as relevant or irrelevant, the image classifier is trained to detect patterns, of arbitrary size, that only appear in relevant images. After training, similar patterns are sought in new images in order to(More)