Bálint Péter Kerekes

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Spontaneous synchronous population activity (SPA) can be detected by electrophysiological methods in cortical slices of epileptic patients, maintained in a physiological medium in vitro. In order to gain additional spatial information about the network mechanisms involved in the SPA generation, we combined electrophysiological studies with two-photon(More)
Standard 3-inch <100> oriented 200-µm-thick p-type silicon wafers polished on both sides were used (Fig.4.) for the probe fabrication process that proceeded in several technological steps (Fig.5.). The pattern definiton consisted of various thin-film depositions to form the bottom insulating layers, the Pt electrode contacts and wires, the passivation(More)
This paper presents multi-electrode arrays for in vivo neural recording applications incorporating the principle of electronic depth control (EDC), i.e., the electronic selection of recording sites along slender probe shafts independently for multiple channels. Two-dimensional (2D) arrays were realized using a commercial 0.5- μm(More)
In this article, we evaluated the electrophysiological performance of a novel, high-complexity silicon probe array. This brain-implantable probe implements a dynamically reconfigurable voltage-recording device, coordinating large numbers of electronically switchable recording sites, referred to as electronic depth control (EDC). Our results show the(More)
Rhythmic slow waves characterize brain electrical activity during natural deep sleep and under anesthesia, reflecting the synchronous membrane potential fluctuations of neurons in the thalamocortical network. Strong evidence indicates that the neocortex plays an important role in the generation of slow wave activity (SWA), however, contributions of(More)
Six patients with rapidly progressive glomerulonephritis were given plasmapheresis and peritoneal dialysis by manual technique. At the start of treatment the patients were in renal failure and all but two were practically anuric. Renal biopsy revealed glomerular sclerosis in 4 cases. One of the patients in whom segmental focal fibrosis was found, went into(More)
A novel silicon-based microelectrode array with oneand two-dimensional variants was developed in the framework of the EUfunded research project NeuroProbes. The electrode array comprises complementary-metal-oxide-semiconductor based integrated circuitry to implement the concept of electronic depth control which is used to select up to 32 recording sites(More)
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