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HLA Class I Allelic Sequence and Conformation Regulate Leukocyte Ig-Like Receptor Binding
The hypothesis that LILR-mediated detection of unfolded versus folded MHC modulates immune responses during infection or inflammation supports the hypothesis that HLA class I recognition due to HLA allelic variation could be a contributing factor in disease.
Evolutionary Relations of Hexanchiformes Deep-Sea Sharks Elucidated by Whole Mitochondrial Genome Sequences
The phylogeny suggested that Hexanchiformes is in the superorder Squalomorphi, Chlamydoselachus anguineus (frilled shark) is the sister species to all other Hexanchiales, and the relations within Hex Anchiformes are well resolved.
Genomic Sequence Analysis of the MHC Class I G/F Segment in Common Marmoset (Callithrix jacchus)
Phylogenetic analysis suggests segmental duplications of units consisting of basically five MHC class I genes, with subsequent expansion/deletion of genes, indicating that this genomic segment was formed in New World monkeys after the split of New World and Old World monkeys.
Nutritional and hormonal regulation of uncoupling protein 2
- T. Yonezawa, Riho Kurata, K. Hosomichi, Azumi Kono, M. Kimura, H. Inoko
- BiologyIUBMB life
- 1 December 2009
Light is shed on the nutritional and hormonal regulation of UCP2 and on its physiological roles that can dissipate metabolic energy as heat as efficiently as UCP1 is open to dispute.
Comparative genome analysis of the major histocompatibility complex (MHC) class I B/C segments in primates elucidated by genomic sequencing in common marmoset (Callithrix jacchus)
Two parts of the Caja-B sequences with 1,079 kb in total are determined and indicate that the MHC-B/C segment has been under permanent selective pressure in the evolution of primates.
Double expression of CD34 and CD117 on bone marrow progenitors is a hallmark of the development of functional mast cell of Callithrix jacchus (common marmoset).
The results suggest that this marmoset system provides a good model for human MC development, similarly to human MCs.