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Combinatorial microRNA target predictions
TLDR
PicTar, a computational method for identifying common targets of micro RNAs, is presented and widespread coordinate control executed by microRNAs is suggested, thus providing evidence for coordinate microRNA control in mammals.
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data
TLDR
It is demonstrated that increasing the number of replicate samples significantly improves detection power over increased sequencing depth, and array-based methods adapted to RNA-seq data perform comparably to methods designed forRNA-seq.
Cell-type-specific signatures of microRNAs on target mRNA expression.
TLDR
The hypothesis that miRNA expression broadly contributes to tissue specificity of mRNA expression in many human tissues is supported.
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