Azat Abdullin

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In the developing hippocampus, GABA exerts depolarizing and excitatory actions and contributes to the generation of neuronal network driven giant depolarizing potentials (GDPs). Here, we studied spike time coding at immature GABAergic synapses and its impact on synchronization of the neuronal network during GDPs in the neonatal (postnatal days P2-6) rat(More)
For 100 days the rats were kept in vertical position, and after histo- and biochemical characteristics of the musc. gastrocnemius (fast) and musc. soleus (slow) were studied. A prolonged static loading was stated to produce increasing number of white and intermediate fibres in the m. gastrocnemius and intermediate fibres in the m. soleus. The fast and slow(More)
Both transmembrane and extracellular cues, one of which is collagen XIII, regulate the formation and function of the neuromuscular synapse, and their absence results in myasthenia. We show that the phenotypical changes in collagen XIII knock-out mice are milder than symptoms in human patients, but the Col13a1-/- mice recapitulate major muscle findings of(More)
Ultrastructural characteristics of the rat skeletal muscle fibers was studied under a prolonged static loading. Disruption of the mitochondrial membranes, desintegration and lysis of myofibrils, desorganization of the T-system and Z-bands were revealed. Destructive processes were accompanied with the physiological reparative regeneration evidenced by a(More)
In the musculus soleus of mature male rats, 6 weeks after thyroidectomy, muscle fibers with a low adenosin triphosphatase activity of myosin decrease in number, as well as the cross section area of the muscle fibers with a moderate and high activity of the enzyme. Optic density of the muscle fibers staining also decreases when succinatedehydrogenase(More)
Program analysis is rapidly changing the way we develop software; one of the more important problems is that of function contract creation, as these contracts can greatly increase the quality and performance of the analysis. However, the predominant way of creating function contracts is their manual development by the end-user. In this paper we present an(More)
Properties of fibronectin, isolated by means of affinity chromatography from blood plasma of suddenly dead persons, were studied. This blood exhibited high fibrinolytic potential and was not capable of clotting due to degradation of fibrinogen. At the same time, fibronectin was also isolated from blood plasma of healthy volunteers. Properties of these(More)
Blood plasma and synovial fluid (SF) of 48 patients with rheumatoid arthritis (RA) were studied. Plasma fibronectin (FN) concentration measured by rocket immunoelectrophoresis was found to be almost the same in patients and in healthy donors (348.6 +/- 16.4 micrograms/ml and 354.3 +/- 10.2 micrograms/ml, respectively. The level of SL FN was shown to rise in(More)
Musculus gastrocnemius and m. soleus in Wistar rats have been studied at a prolonged static loading. The static loading does not produce any changes in the animals' body mass and in m. gastrocnemius, while the mass of m. soleus statistically differs after the experiment. There are some changes in relative amount of muscle fibres: in m. gastrocnemius the(More)