Azadeh Mofid

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BACKGROUND Gastro-oesophageal reflux disease (GERD) is a growing health-care problem with variable distribution. AIM To assess GERD prevalence and risk factors and their possible correlation with pathophysiology in a population-based study. METHODS Individuals aged 18-65 years were enrolled through random cluster sampling in Tehran. Previously validated(More)
BACKGROUND Gastroesophageal reflux disease is a common and chronic disorder but long term, prospective studies of the fate of patients seeking medical advice are scarce. This is especially prominent when looking at non-erosive reflux disease (NERD) patients. METHODS We designed a prospective cohort to assess the long term outcome of GERD patients(More)
BACKGROUND Increased duodenal intraepithelial lymphocytes is a key histological finding in celiac disease. Available studies suggest a wide normal range (10 - 40 intraepithelial lymphocytes /100 epithelial cells, EC). We assessed the normal range of distal duodenal intraepithelial lymphocytes. METHODS Biopsies from the normal-looking distal duodenum from(More)
BACKGROUND Gastro-esophageal reflux disease (GERD) has become very common in the past three decades. The reason for this, as well as its exact pathophysiologic mechanisms are yet unknown. In this ecologic study we assessed the relation between water nitrate content and prevalence of GERD in Tehran, Iran. METHODS We determined the prevalence of acid(More)
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