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  • Venkata Lokesh Battula, Kurt W. Evans, +8 authors Sendurai A Mani
  • Medicine, Biology
  • Stem cells
  • 2010 (First Publication: 1 August 2010)
  • The epithelial-to-mesenchymal transition (EMT) is an embryonic process that becomes latent in most normal adult tissues. Recently, we have shown that induction of EMT endows breast epithelial cellsContinue Reading
  • George Sflomos, Valérian Dormoy, +10 authors Cathrin Brisken
  • Biology, Medicine
  • Cancer cell
  • 2016 (First Publication: 1 March 2016)
  • Seventy-five percent of breast cancers are estrogen receptor α positive (ER⁺). Research on these tumors is hampered by lack of adequate in vivo models; cell line xenografts require non-physiologicalContinue Reading
  • Maryse Fiche, Valentina Scabia, +8 authors Cathrin Brisken
  • Biology, Medicine
  • The Journal of pathology
  • 2019 (First Publication: 1 March 2019)
  • Estrogen receptor α-positive (ER-positive) or 'luminal' breast cancers were notoriously difficult to establish as patient-derived xenografts (PDXs). We and others recently demonstrated that theContinue Reading