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Resistance-Nodulation-Division (RND) efflux pumps are one of the most important determinants of multidrug resistance (MDR) in Gram-negative bacteria. With an ever increasing number of Gram-negative clinical isolates exhibiting MDR phenotypes as a result of the activity of RND pumps, it is clear that the design of novel effective clinical strategies against(More)
BACKGROUND The Pseudomonas aeruginosa MexEF-OprN efflux pump confers resistance to clinically significant antibiotics. Regulation of mexEF-oprN operon expression is multifaceted with the MexT activator being one of the most prominent regulatory proteins. METHODOLOGY We have exploited the impaired metabolic fitness of a P. aeruginosa mutant strain lacking(More)
In recent years, Data Mining is an important aspect for generating association rules among the large number of itemsets. Association Rule Mining is the method for discovering interesting relations between variables in large databases. It is considered as one of the important tasks of data mining intended towards decision making. Genetic algorithm (GA) based(More)
—This work presents joint subcarrier, power and bit allocation schemes for multiuser OFDM based overlay cognitive radio under constraints on primary user throughput loss and total secondary user transmitted power. Closed form for expressions for the optimal power and bit allocations are initially derived. Subsequently, optimal and suboptimal algorithms to(More)
We report here a genome sequence for Rhodococcus sp. isolate UM008 isolated from the renal/interrenal tissue of the winter skate Leucoraja ocellata Genome sequence analysis suggests that Rhodococcus bacteria may act in a novel mutualistic relationship with their elasmobranch host, serving as biocatalysts in the steroidogenic pathway of(More)
Acinetobacter baumannii, a Gram-negative opportunistic pathogen, is known to cause multidrug resistant infections. This organism has primarily been isolated from clinical environments and its environmental reservoirs remain largely unknown. In the present study, we recovered seven isolates of A. baumannii growing under conditions selective for Campylobacter(More)
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