Ayumu Sugiyama

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CELF/Bruno-like proteins play multiple roles, including the regulation of alternative splicing and translation. These RNA-binding proteins contain two RNA recognition motif (RRM) domains at the N-terminus and another RRM at the C-terminus. CUGBP2 is a member of this family of proteins that possesses several alternatively spliced exons. The present study(More)
What is structure of water surrounding proteins remains as one of fundamental unsolved problems of science. Methods in biophysics only provide qualitative description of the structure and thus clarifying the collective phenomena of a huge number of water molecules is still beyond intuition in biophysics. We introduce a simulation-based data mining approach(More)
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