Ayman Saber Mohamed

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Oxidative stress is a common mechanism contributing to the initiation and progression of hepatic damage. Hence there is a great demand for the development of agents with potent antioxidant effect. The aim of the present study is to evaluate the efficacy of Holothuria atra extract (HaE) as an antioxidant against 7,12-dimethylbenz[a]anthracene- (DMBA-)(More)
OBJECTIVE The aim of our study was to assess the complications of hepatic fibrosis associated with bile duct ligation and the potential curative role of sepia ink extract in hepatic damage induced by bile duct ligation. METHODS Rattus norvegicus rats were divided into 3 groups: Sham-operated group, model rats that underwent common bile duct ligation(More)
BACKGROUND Acute Renal Failure (ARF) in patients with cirrhosis is one of the most frequently encountered complications of obstructive jaundice. Marine organisms from the Mediterranean Coast of Egypt are considered potential sources of bioactive molecules. The present study was undertaken to explore the curative effects of Holothuria arenicola extract (HaE)(More)
BACKGROUND Diabetes mellitus is a main reason of morbidity and mortality worldwide. In recent years great attention has been paid to bioactivity of natural products due to their potential pharmacological utilization. Echinochrome is natural compound isolated from sea urchins and possesses many biological effects. The hypoglycemic activity of echinochrome(More)
BACKGROUND Diabetes mellitus is one of the most public metabolic disorders. It is mainly classified into type 1 and type 2. Echinochrome is a pigment from sea urchins that has antioxidant, anti-microbial, anti-inflammatory and chelating abilities. AIMS The present study aimed to investigate the anti-diabetic mechanisms of echinochrome pigment in(More)
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