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BACKGROUND In a number of studies prolonged breastfeeding was associated with a higher risk of undernutrition, although most of these studies are limited by their cross-sectional design which does not allow examination of temporal relationships between full weaning and undernutrition. METHODS The relationship between prolonged breastfeeding and child(More)
We examined prospectively the relation between malnutrition and mortality among Sudanese children. A cohort of 28753 children between the ages of 6 mo and 6 y was examined every 6 mo for 18 mo. Two hundred thirty-two children died during 18 mo of follow-up (480624 child-months). Low weight-for-height was associated with an increased risk of mortality (P <(More)
The prevalence of eye signs and symptoms of vitamin A deficiency was determined among 29,615 Sudanese children between 6 and 72 mo of age, in five rural areas of Khartoum and Gezira provinces. Of all children, 2.9% were vitamin A deficient, and of these > 90% had Bitot's spots. Bivariate associations were found between xerophthalmia and the rural councils(More)
We examined prospectively the associations between dietary vitamin A intake, nondietary factors and growth in 8174 Sudanese children ages 6-72 mo who were stunted at the start of follow-up. All subjects were weighed and measured at baseline and at 6-mo intervals for 18 mo of follow-up. Dietary vitamin A intake during the prior 24 h was assessed using recall(More)
Increased consumption of dietary vitamin A is advocated as a long-term solution to vitamin A deficiency. We prospectively examined the relationship of dietary vitamin A intake and child mortality among 28,753 Sudanese children aged 6 mo to 6 y, who participated in a trial of vitamin A supplementation. After 18 mo of follow-up, 232 children died. Total(More)
Previous studies of the effect of 6-monthly vitamin A supplementation on child mortality have given conflicting results. In other trials, more frequent doses of vitamin A have significantly reduced mortality among children at risk of vitamin A deficiency. We have done a double-blind, placebo-controlled trial of vitamin A supplementation in the Sudan among(More)
OBJECTIVE The aim of the study was to examine the relationships between nutritional status and diarrhoea and respiratory infections. DESIGN Prospective cohort study within the framework of a randomized double-blind placebo-controlled intervention trial. SETTING In rural communities in the Khartoum and Gezira regions, in Northern Sudan. SUBJECTS 28,753(More)
OBJECTIVES This study assessed the effect of vitamin A supplementation at 6-month intervals on child growth. METHODS Sudanese children (n = 28,740) 6 to 72 months of age were weighed and measured at baseline and at each of three follow-up visits. RESULTS Periodic vitamin A supplementation had no effect on the rate of weight or height gain in the total(More)
The relationship of vitamin A deficiency and child survival has been documented in a number of studies but not in others, yet the relationship of vitamin A with child morbidity remains controversial. We prospectively examined the relationship of dietary vitamin A intake and the incidences of diarrhea and respiratory infection among 28,753 Sudanese children(More)
Severe deficits in ponderal and linear growth are problems of major public health significance among children in developing countries. We prospectively examined the association of dietary vitamin A intake with child growth among 28,740 Sudanese children ages 6-72 months. At baseline and at each 6-month visit, all subjects were weighed and measured. Dietary(More)