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Neural activity during repeated presentations of a sensory stimulus exhibits considerable trial-by-trial variability. Previous studies have reported that trial-by-trial neural variability is reduced (quenched) by the presentation of a stimulus. However, the functional significance and behavioral relevance of variability quenching and the potential(More)
Attention Deficit Hyperactivity Disorder (ADHD) has been described as a disorder where frequent lapses of attention impair the ability of an individual to focus/attend in a sustained manner, thereby generating abnormally large intra-individual behavioral variability across trials. Indeed, increased reaction time (RT) variability is a fundamental behavioral(More)
A wide variety of sensory studies have shown that cortical neural activity varies dramatically across trials. This trial-by-trial neural variability is relatively large in the pre-stimulus period and considerably smaller (quenched) following stimulus presentation. Neural variability affects behaviour. For example, perceptual performance is better on trials(More)
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