Ayako Kohori

Learn More
F1-adenosine triphosphatase (ATPase) is an ATP-driven rotary molecular motor in which the central gamma subunit rotates inside a cylinder made of three alpha and three beta subunits alternately arranged. The rotor shaft, an antiparallel alpha-helical coiled coil of the amino and carboxyl termini of the gamma subunit, deeply penetrates the central cavity of(More)
F1-ATPase is a powerful rotary molecular motor that can rotate an object several hundred times as large as the motor itself against the viscous friction of water. Forced reverse rotation has been shown to lead to ATP synthesis, implying that the mechanical work against the motor's high torque can be converted into the chemical energy of ATP. The minimal(More)
F(1)-ATPase is an ATP-driven rotary molecular motor in which the central gamma-subunit rotates inside the cylinder made of alpha(3)beta(3) subunits. The amino and carboxy termini of the gamma-subunit form the axle, an alpha-helical coiled coil that deeply penetrates the stator cylinder. We previously truncated the axle step by step, starting with the longer(More)
The present study investigated whether transplantation of autologous adipose-derived stem cells (ASCs) administered into the systemic circulation of a mouse with chronic liver injury provides therapeutic efficacy in the absence of any undesirable side effects. The ASCs used were isolated from mice with the same genetic background as the recipient mice and(More)
  • Ayako Kohori
  • Shinrigaku kenkyu : The Japanese journal of…
  • 2010
This study elucidates processes of coping with work-family conflicts in double-income couples with children. Eight stories of dilemmas concerning work-family conflicts were constructed. Regular employees (N=20) were instructed to narrate the parts of the story in which they thought about how to cope with work-family conflict situations. The protocol(More)
Mesenchymal stem cells (MSCs) have shown extreme clinical promise as a therapeutic regenerative system in the treatment of numerous types of diseases. A recent report, however, documented lethal pulmonary thromboembolism in a patient following the administration of adipose-derived MSCs (ADSCs). In our study, we designed experiments to examine the role of(More)
Proceedings of the 2nd Meeting of the Asian Cellular Therapy Organization; Published online 30 Nov 2011 Adult acute lymphoblastic leukemia (ALL) is one of the intractable diseases in hematological malignancies, showing about 30% long-term survival by intensive chemotherapies with high incidence of relapse. Allogeneic hematopoietic stem cell transplantation(More)
Proceedings of the 2nd Meeting of the Asian Cellular Therapy Organization; Published online 30 Nov 2011 [Background]Mesenchymal stem cells (MSCs) have been highlighted in the field of regenerative medicine for their availability and multipotency. However, it has been reported that MSC may associate with cell-infusion-related events including thromboembolism(More)
F(1)-ATPase is an ATP-driven rotary molecular motor in which the central γ-subunit rotates inside a cylinder made of α(3)β(3) subunits. The amino and carboxyl termini of the γ rotor form a coiled coil of α-helices that penetrates the stator cylinder to serve as an axle. Crystal structures indicate that the axle is supported by the stator at two positions,(More)
  • 1