Ayako Kawashima

Learn More
OBJECT The L-type Ca++ channel antagonists like nimodipine have limited efficacy against vasospasm after subarachnoid hemorrhage (SAH). The authors tested the hypothesis that this is because SAH alters these channels, rendering them less responsible for contraction. METHODS Basilar artery smooth muscle cells were isolated 4, 7, and 21 days after SAH in(More)
Electrophysiological and molecular characteristics of voltage-dependent calcium (Ca(2+)) channels were studied using whole-cell patch clamp, polymerase chain reaction and Western blotting in smooth muscle cells freshly isolated from dog basilar artery. Inward currents evoked by depolarizing steps from a holding potential of -50 or -90 mV in 10 mm barium(More)
Clinical evidence suggests that factors other than cerebral vasospasm, such as delayed neuronal and astrocytic cell death, may play a role in the poor prognosis of patients with subarachnoid hemorrhage (SAH). Here we examined this using immunohistochemistry and confocal microscopy in 3 different brain areas in a dog model of SAH. Using antibodies against(More)
We reported a rare case of cervical glioblastoma with intracranial dissemination at an early stage of clinical course and reviewed the literature. An 8-year-old girl presented with failure of vision 3 months prior to admission to our hospital. Neurological examination on admission disclosed no definitive abnormalities except for bilateral visual disturbance(More)
This study proposes methods for the support of radiotherapy planning for dynamic tumor-tracking irradiation for lung tumors. It aims to simulate the deformation of the lung caused by respiration and to visualize the result as DRRs (Digitally Reconstructed Radiographs) in real time. Our lungdeformation model treats the lung as an elastic object and analyzes(More)
Microbioreactors are effective for high-throughput production of expensive products from small amounts of substrates. Lipases are versatile enzymes for chiral syntheses, and are highly activated when immobilized in alkyl-substituted silicates by the sol-gel method. For practical application of sol-gel immobilized lipases to a flow system, a microbioreactor(More)
1. Haffer, J.: Science 165, 131 (1969) 2. Van der Hammen, T.: Geol. Mijnbouw 51, 641 (1972) 3. Damuth, J.E., Flood, R.D.: Geo-Marine Lett. 3, 109 (1984) 4. Sioli, H.: Amazonien. Grundlagen der Okologie des gr613ten tropischen Waldlandes. Stuttgart: Wiss. Verlagsgesellschaft 1983 5. Irion, G.: Trop. Ecol. 23 (1), 76 (1982) 6. Milliman, J.D., Barretto, H.T.:(More)
  • 1