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Sirtuin 1 Retards Hyperphosphatemia-Induced Calcification of Vascular Smooth Muscle Cells
- Aya Takemura, K. Iijima, +6 authors Y. Ouchi
- Biology, Medicine
- Arteriosclerosis, thrombosis, and vascular…
- 1 September 2011
Objective— Arterial calcification is associated with cardiovascular disease as a complication of advanced atherosclerosis. Aged vascular cells manifest some morphological features of a senescent… Expand
[Molecular mechanism of vascular aging: impact of vascular smooth muscle cell calcification via cellular senescence].
Atherosclerotic vascular damage associated with aging manifest several features, namely atherosis, sclerosis and calcified change, finally leading to cardiovascular (CV) events. Accumulating recent… Expand