Aya Kunitomi

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We investigated whether gp34, the ligand of OX40, expressed on EC is involved in costimulation of T cells. Normal CD4+ T cells were stimulated with anti-CD3-coated beads, phytohemagglutinin (PHA), or concanavalin A (Con A) in the presence or absence of irradiated human umbilical vein endothelial cells (HUVEC). Stimulation of T cells with each of these(More)
Parathyroid hormone-related protein (PTHrP) is considered to be one of the main causes of hypercalcemia associated with adult T-cell leukemia (ATL). To clarify the role of PTHrP and bone remodeling in the development of hypercalcemia in ATL, we examined the SCID mouse model of ATL that has previously been shown to mimic the disease in humans. Using this(More)
The case is a 75-year-old man, who underwent curative resection for the upper part of stomach cancer (Stage II), and was without a recurrence for two years. The patient had been well until September 2006, when CT examination revealed a 5 cm tumor in the rectovesical pouch. The tumor was histologically diagnosed as a peritoneal metastasis of gastric cancer(More)
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